attomol® Caleidoscan 100 - Automated Fluorescence Imager

attomol® Caleidoscan 100 – Automated Fluorescence Imager for Bead Assays & Multiplex Analyses

The attomol® Caleidoscan 100 (CS100) is a fully automated fluorescence imager for the rapid and standardized acquisition of fluorescent micro-objects. Developed for multiplex-capable bead assays, it combines precise fluorescence optics, motorized sample guidance, and automated software evaluation for efficient, reproducible analyses. The system is ideal for diagnostic laboratories, research institutions, and industrial quality assurance where high sensitivity, speed, and standardization are required.

Highlights

• Automated fluorescence imaging with three measurement channels (blue, green, red)
• Acquisition of a complete 96-well microtiter plate in approx. 15 minutes
• Precise microscope optics for high sensitivity and reproducible results
• Motorized x/y/z-axes with autofocus and standardized sample positioning
• Multiband filter system for fast acquisition without filter changes
• Control and evaluation via attomol® Caleidopro software
• Automatic bead detection, classification, and evaluation of up to 18 bead populations
• Stable, robust device design for routine laboratory operation
• Optimal for multiplex assays, serological tests, and research applications

Technical Highlights

• Three fluorescence channels: blue (460 nm), green (530 nm), red (640 nm)
• Sample throughput: up to 96 samples per measurement cycle
• Measurement time: approx. 15 minutes per 96-well plate
• Optics: High-resolution microscope optics for precise fluorescence detection
• Illumination: long-lasting, stable high-power LEDs
• Motorization: x/y motorized stage, z-axis with autofocus
• Software: attomol® Caleidopro for image acquisition, analysis, reporting, and LIMS export
• Dimensions: approx. 37 × 63 × 48 cm
• Weight: approx. 42 kg
• Power supply: 24 V DC (via external power adapter)

Typical Applications

• Autoimmune diagnostics (ANA, CCP, specific autoantibody profiles)
• Infection diagnostics (Borrelia, Yersinia, etc., depending on bead assay)
• Multiplex bead assays with up to 18 parameters per well
• Research & development in immunology, molecular biology, and protein analytics
• Food analysis, hygiene control, and screening applications
• Routine laboratories with high sample volumes and a need for reproducible results

Software Functions – attomol® Caleidopro

• Control of all motorized components of the CS100
• Automatic bead classification by size and fluorescence code
• Calculation of analytes based on red fluorescence signals
• Integrated positive, negative, and sample controls per well
• Output of semi-quantitative ratios (measured value to cut-off)
• Complete report generation (PDF) and data export to LIMS
• Standardized, digitally documentable workflows

Summary

The attomol® Caleidoscan 100 offers a powerful combination of automated fluorescence imaging, precise optics, and software-supported data analysis. The system enables reliable, fast, and reproducible multiplex bead assays and is ideally suited for modern diagnostic and research laboratories that require the highest level of efficiency and standardization.